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Preclinical PET Neuroimaging of [(11)C]Bexarotene

Activation of retinoid X receptors (RXRs) has been proposed as a therapeutic mechanism for the treatment of neurodegeneration, including Alzheimer's and Parkinson's diseases. We previously reported radiolabeling of a Food and Drug Administration-approved RXR agonist, bexarotene, by copper-...

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Detalles Bibliográficos
Autores principales: Rotstein, Benjamin H., Placzek, Michael S., Krishnan, Hema S., Pekošak, Aleksandra, Collier, Thomas Lee, Wang, Changning, Liang, Steven H., Burstein, Ethan S., Hooker, Jacob M., Vasdev, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011434/
https://www.ncbi.nlm.nih.gov/pubmed/27553293
http://dx.doi.org/10.1177/1536012116663054