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ErbB2 signaling at the crossing between heart failure and cancer

The dual role of ErbB2 (or HER-2) in tumor growth and in physiological adaptive reactions of the heart positions ErbB2 at the intersection between cancer and chronic heart failure. Accordingly, ErbB2-targeted inhibitory therapy of cancer may lead to ventricular dysfunction, and activation of ErbB2 f...

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Detalles Bibliográficos
Autores principales: Vermeulen, Zarha, Segers, Vincent F. M., De Keulenaer, Gilles W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011481/
https://www.ncbi.nlm.nih.gov/pubmed/27596216
http://dx.doi.org/10.1007/s00395-016-0576-z