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ErbB2 signaling at the crossing between heart failure and cancer
The dual role of ErbB2 (or HER-2) in tumor growth and in physiological adaptive reactions of the heart positions ErbB2 at the intersection between cancer and chronic heart failure. Accordingly, ErbB2-targeted inhibitory therapy of cancer may lead to ventricular dysfunction, and activation of ErbB2 f...
Autores principales: | Vermeulen, Zarha, Segers, Vincent F. M., De Keulenaer, Gilles W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011481/ https://www.ncbi.nlm.nih.gov/pubmed/27596216 http://dx.doi.org/10.1007/s00395-016-0576-z |
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