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Differential heme release from various hemoglobin redox states and the upregulation of cellular heme oxygenase‐1

Despite advances in our understanding of the oxidative pathways mediated by free hemoglobin (Hb), the precise contribution of its highly reactive redox forms to tissue and organ toxicities remains ambiguous. Heme, a key degradation byproduct of Hb oxidation, has recently been recognized as a damage‐...

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Detalles Bibliográficos
Autores principales: Kassa, Tigist, Jana, Sirsendu, Meng, Fantao, Alayash, Abdu I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011486/
https://www.ncbi.nlm.nih.gov/pubmed/27642551
http://dx.doi.org/10.1002/2211-5463.12103