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Differential heme release from various hemoglobin redox states and the upregulation of cellular heme oxygenase‐1
Despite advances in our understanding of the oxidative pathways mediated by free hemoglobin (Hb), the precise contribution of its highly reactive redox forms to tissue and organ toxicities remains ambiguous. Heme, a key degradation byproduct of Hb oxidation, has recently been recognized as a damage‐...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011486/ https://www.ncbi.nlm.nih.gov/pubmed/27642551 http://dx.doi.org/10.1002/2211-5463.12103 |