Cargando…

Suppression of liver Apo E secretion leads to HDL/cholesterol immaturity in rats administered ethinylestradiol

Ethinylestradiol (EE), a main component of the combined oral contraceptive pill, is associated with an increased risk of arterial diseases. However, the toxicity mechanism of EE is poorly understood. In this study, we found that the exposure to EE reduced the serum apolipoprotein E (Apo E) level and...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamaguchi, Kosuke, Ishii, Mariko, Maeda, Naoyuki, Iwano, Hidetomo, Yokota, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011491/
https://www.ncbi.nlm.nih.gov/pubmed/27642556
http://dx.doi.org/10.1002/2211-5463.12098