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Suppression of liver Apo E secretion leads to HDL/cholesterol immaturity in rats administered ethinylestradiol
Ethinylestradiol (EE), a main component of the combined oral contraceptive pill, is associated with an increased risk of arterial diseases. However, the toxicity mechanism of EE is poorly understood. In this study, we found that the exposure to EE reduced the serum apolipoprotein E (Apo E) level and...
Autores principales: | Yamaguchi, Kosuke, Ishii, Mariko, Maeda, Naoyuki, Iwano, Hidetomo, Yokota, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011491/ https://www.ncbi.nlm.nih.gov/pubmed/27642556 http://dx.doi.org/10.1002/2211-5463.12098 |
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