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Smad4 suppresses the tumorigenesis and aggressiveness of neuroblastoma through repressing the expression of heparanase

Heparanase (HPSE) is the only endo-β-D-glucuronidase that is correlated with the progression of neuroblastoma (NB), the most common extracranial malignancy in childhood. However, the mechanisms underlying HPSE expression in NB still remain largely unknown. Herein, through analyzing cis-regulatory el...

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Detalles Bibliográficos
Autores principales: Qu, Hongxia, Zheng, Liduan, Jiao, Wanju, Mei, Hong, Li, Dan, Song, Huajie, Fang, Erhu, Wang, Xiaojing, Li, Shiwang, Huang, Kai, Tong, Qiangsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011643/
https://www.ncbi.nlm.nih.gov/pubmed/27595937
http://dx.doi.org/10.1038/srep32628