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CCL2, but not its receptor, is essential to restrict immune privileged central nervous system‐invasion of Japanese encephalitis virus via regulating accumulation of CD11b(+) Ly‐6C(hi) monocytes

Japanese encephalitis virus (JEV) is a re‐emerging zoonotic flavivirus that poses an increasing threat to global health and welfare due to rapid changes in climate and demography. Although the CCR2–CCL2 axis plays an important role in trafficking CD11b(+) Ly‐6C(hi) monocytes to regulate immunopathol...

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Detalles Bibliográficos
Autores principales: Kim, Jin Hyoung, Patil, Ajit Mahadev, Choi, Jin Young, Kim, Seong Bum, Uyangaa, Erdenebileg, Hossain, Ferdaus Mohd Altaf, Park, Sang‐Youel, Lee, John Hwa, Kim, Koanhoi, Eo, Seong Kug
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011677/
https://www.ncbi.nlm.nih.gov/pubmed/27260136
http://dx.doi.org/10.1111/imm.12626