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Evidence for the mechanosensor function of filamin in tissue development

Cells integrate mechanical properties of their surroundings to form multicellular, three-dimensional tissues of appropriate size and spatial organisation. Actin cytoskeleton-linked proteins such as talin, vinculin and filamin function as mechanosensors in cells, but it has yet to be tested whether t...

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Detalles Bibliográficos
Autores principales: Huelsmann, Sven, Rintanen, Nina, Sethi, Ritika, Brown, Nicholas H., Ylänne, Jari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011733/
https://www.ncbi.nlm.nih.gov/pubmed/27597179
http://dx.doi.org/10.1038/srep32798