Up-regulation of miR-370-3p restores glioblastoma multiforme sensitivity to temozolomide by influencing MGMT expression

MicroRNAs (miRNA) are believed to play an important role in glioblastoma multiforme (GBM)chemotherapy. Our study aims to investigate potential miRNA biomarkers in GBM. Sixty GBM patients, which were given temozolomide (TMZ) chemotherapy and recurrent radiotherapy, were recruited. miRNA array was per...

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Detalles Bibliográficos
Autores principales: Gao, Yong-tao, Chen, Xiao-bing, Liu, Hong-lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011744/
https://www.ncbi.nlm.nih.gov/pubmed/27595933
http://dx.doi.org/10.1038/srep32972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011744/
https://www.ncbi.nlm.nih.gov/pubmed/27595933
http://dx.doi.org/10.1038/srep32972

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