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ACT‐ONE ‐ ACTION at last on cancer cachexia by adapting a novel action beta‐blocker

Novel action beta‐blockers combine many different pharmacological effects. The espindolol exhibits effects through β and central 5‐HT1α receptors to demonstrate pro‐anabolic, anti‐catabolic, and appetite‐stimulating actions. In the ACT‐ONE trial, espindolol reversed weight loss and improved handgrip...

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Detalles Bibliográficos
Autores principales: Lainscak, Mitja, Laviano, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011815/
https://www.ncbi.nlm.nih.gov/pubmed/27625919
http://dx.doi.org/10.1002/jcsm.12136