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Revealing misassembled segments in the bovine reference genome by high resolution linkage disequilibrium scan
BACKGROUND: Misassembly signatures, created by shuffling the order of sequences while assembling a genome, can be detected by the unexpected behavior of marker linkage disequilibrium (LD) decay. We developed a heuristic process to identify misassembly signatures, applied it to the bovine reference g...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011828/ https://www.ncbi.nlm.nih.gov/pubmed/27595709 http://dx.doi.org/10.1186/s12864-016-3049-8 |