Revealing misassembled segments in the bovine reference genome by high resolution linkage disequilibrium scan

BACKGROUND: Misassembly signatures, created by shuffling the order of sequences while assembling a genome, can be detected by the unexpected behavior of marker linkage disequilibrium (LD) decay. We developed a heuristic process to identify misassembly signatures, applied it to the bovine reference g...

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Detalles Bibliográficos
Autores principales: Utsunomiya, Adam T. H., Santos, Daniel J. A., Boison, Solomon A., Utsunomiya, Yuri T., Milanesi, Marco, Bickhart, Derek M., Ajmone-Marsan, Paolo, Sölkner, Johann, Garcia, José F., da Fonseca, Ricardo, da Silva, Marcos V. G. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011828/
https://www.ncbi.nlm.nih.gov/pubmed/27595709
http://dx.doi.org/10.1186/s12864-016-3049-8

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