Combining Shigella Tn-seq data with gold-standard E. coli gene deletion data suggests rare transitions between essential and non-essential gene functionality

BACKGROUND: Gene essentiality - whether or not a gene is necessary for cell growth - is a fundamental component of gene function. It is not well established how quickly gene essentiality can change, as few studies have compared empirical measures of essentiality between closely related organisms. RE...

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Detalles Bibliográficos
Autores principales: Freed, Nikki E., Bumann, Dirk, Silander, Olin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011829/
https://www.ncbi.nlm.nih.gov/pubmed/27599549
http://dx.doi.org/10.1186/s12866-016-0818-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011829/
https://www.ncbi.nlm.nih.gov/pubmed/27599549
http://dx.doi.org/10.1186/s12866-016-0818-0

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