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Modelling concentrations of antimicrobial drugs: comparative pharmacokinetics of cephalosporin antimicrobials and accuracy of allometric scaling in food-producing and companion animals

BACKGROUND: To optimize antimicrobial dosing in different animal species, pharmacokinetic information is necessary. Due to the plethora of cephalosporin antimicrobials and animal species in which they are used, assessment of pharmacokinetics in all species is unfeasible. In this study we aimed to de...

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Detalles Bibliográficos
Autores principales: Taverne, Femke J., van Geijlswijk, Ingeborg M., Heederik, Dick J. J., Wagenaar, Jaap A., Mouton, Johan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011836/
https://www.ncbi.nlm.nih.gov/pubmed/27596044
http://dx.doi.org/10.1186/s12917-016-0817-2