Viral deep sequencing needs an adaptive approach: IRMA, the iterative refinement meta-assembler

BACKGROUND: Deep sequencing makes it possible to observe low-frequency viral variants and sub-populations with greater accuracy and sensitivity than ever before. Existing platforms can be used to multiplex a large number of samples; however, analysis of the resulting data is complex and involves sep...

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Detalles Bibliográficos
Autores principales: Shepard, Samuel S., Meno, Sarah, Bahl, Justin, Wilson, Malania M., Barnes, John, Neuhaus, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011931/
https://www.ncbi.nlm.nih.gov/pubmed/27595578
http://dx.doi.org/10.1186/s12864-016-3030-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011931/
https://www.ncbi.nlm.nih.gov/pubmed/27595578
http://dx.doi.org/10.1186/s12864-016-3030-6

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