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Viral deep sequencing needs an adaptive approach: IRMA, the iterative refinement meta-assembler
BACKGROUND: Deep sequencing makes it possible to observe low-frequency viral variants and sub-populations with greater accuracy and sensitivity than ever before. Existing platforms can be used to multiplex a large number of samples; however, analysis of the resulting data is complex and involves sep...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011931/ https://www.ncbi.nlm.nih.gov/pubmed/27595578 http://dx.doi.org/10.1186/s12864-016-3030-6 |