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Selection of Plasmodium falciparum pfcrt and pfmdr1 polymorphisms after treatment with artesunate–amodiaquine fixed dose combination or artemether–lumefantrine in Liberia

BACKGROUND: Plasmodium falciparum uncomplicated malaria can successfully be treated with an artemisinin-based combination therapy (ACT). However resistance is spreading to the different ACT compounds; the artemisinin derivative and the partner drug. Studies of P. falciparum polymorphisms associated...

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Detalles Bibliográficos
Autores principales: Otienoburu, Sabina Dahlström, Maïga-Ascofaré, Oumou, Schramm, Birgit, Jullien, Vincent, Jones, Joel J., Zolia, Yah M., Houzé, Pascal, Ashley, Elizabeth A., Kiechel, Jean-René, Guérin, Philippe J., Le Bras, Jacques, Houzé, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011943/
https://www.ncbi.nlm.nih.gov/pubmed/27596849
http://dx.doi.org/10.1186/s12936-016-1503-3