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Accuracy of preimplantation genetic screening (PGS) is compromised by degree of mosaicism of human embryos

BACKGROUND: To preclude transfer of aneuploid embryos, current preimplantation genetic screening (PGS) usually involves one trophectoderm biopsy at blastocyst stage, assumed to represent embryo ploidy. Whether one such biopsy can correctly assess embryo ploidy has recently, however, been questioned....

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Detalles Bibliográficos
Autores principales: Gleicher, Norbert, Vidali, Andrea, Braverman, Jeffrey, Kushnir, Vitaly A., Barad, David H., Hudson, Cynthia, Wu, Yang-Guan, Wang, Qi, Zhang, Lin, Albertini, David F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011996/
https://www.ncbi.nlm.nih.gov/pubmed/27595768
http://dx.doi.org/10.1186/s12958-016-0193-6