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Accuracy of preimplantation genetic screening (PGS) is compromised by degree of mosaicism of human embryos
BACKGROUND: To preclude transfer of aneuploid embryos, current preimplantation genetic screening (PGS) usually involves one trophectoderm biopsy at blastocyst stage, assumed to represent embryo ploidy. Whether one such biopsy can correctly assess embryo ploidy has recently, however, been questioned....
Autores principales: | Gleicher, Norbert, Vidali, Andrea, Braverman, Jeffrey, Kushnir, Vitaly A., Barad, David H., Hudson, Cynthia, Wu, Yang-Guan, Wang, Qi, Zhang, Lin, Albertini, David F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011996/ https://www.ncbi.nlm.nih.gov/pubmed/27595768 http://dx.doi.org/10.1186/s12958-016-0193-6 |
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