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Donor age and C1orf132/MIR29B2C determine age-related methylation signature of blood after allogeneic hematopoietic stem cell transplantation

BACKGROUND: Our recent study demonstrated that DNA methylation status in a set of CpGs located in ELOVL2, C1orf132, TRIM59, KLF14, and FHL2 can accurately predict calendar age in blood. In the present work, we used these markers to evaluate the effect of allogeneic hematopoietic stem cell transplant...

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Detalles Bibliográficos
Autores principales: Spólnicka, Magdalena, Piekarska, Renata Zbieć, Jaskuła, Emilia, Basak, Grzegorz W., Jacewicz, Renata, Pięta, Agnieszka, Makowska, Żanetta, Jedrzejczyk, Maciej, Wierzbowska, Agnieszka, Pluta, Agnieszka, Robak, Tadeusz, Berent, Jarosław, Branicki, Wojciech, Jędrzejczak, Wiesław, Lange, Andrzej, Płoski, Rafał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012039/
https://www.ncbi.nlm.nih.gov/pubmed/27602173
http://dx.doi.org/10.1186/s13148-016-0257-7