Cargando…

CD147 promotes cell motility via upregulation of p190-B RhoGAP in hepatocellular carcinoma

BACKGROUND: The acquisition of inappropriate migratory feature is crucial for tumor metastasis. Rho-family GTPases including RhoA are molecular switches that play critical roles in regulating cell movement. We investigated the molecular mechanism underlying CD147 induced RhoA deactivation in hepatoc...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Ruo, Wang, Shi-Jie, Zhang, Yang, Hou, Rong, Jiang, Jian-Li, Cui, Hong-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012051/
https://www.ncbi.nlm.nih.gov/pubmed/27601938
http://dx.doi.org/10.1186/s12935-016-0344-z