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CD147 promotes cell motility via upregulation of p190-B RhoGAP in hepatocellular carcinoma

BACKGROUND: The acquisition of inappropriate migratory feature is crucial for tumor metastasis. Rho-family GTPases including RhoA are molecular switches that play critical roles in regulating cell movement. We investigated the molecular mechanism underlying CD147 induced RhoA deactivation in hepatoc...

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Detalles Bibliográficos
Autores principales: Chen, Ruo, Wang, Shi-Jie, Zhang, Yang, Hou, Rong, Jiang, Jian-Li, Cui, Hong-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012051/
https://www.ncbi.nlm.nih.gov/pubmed/27601938
http://dx.doi.org/10.1186/s12935-016-0344-z

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