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CD147 promotes cell motility via upregulation of p190-B RhoGAP in hepatocellular carcinoma
BACKGROUND: The acquisition of inappropriate migratory feature is crucial for tumor metastasis. Rho-family GTPases including RhoA are molecular switches that play critical roles in regulating cell movement. We investigated the molecular mechanism underlying CD147 induced RhoA deactivation in hepatoc...
Autores principales: | Chen, Ruo, Wang, Shi-Jie, Zhang, Yang, Hou, Rong, Jiang, Jian-Li, Cui, Hong-Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012051/ https://www.ncbi.nlm.nih.gov/pubmed/27601938 http://dx.doi.org/10.1186/s12935-016-0344-z |
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