Modification of platinum sensitivity by KEAP1/NRF2 signals in non-small cell lung cancer

BACKGROUND: The objective of this study was to evaluate the effect of platinum-based drugs on nuclear-factor erythroid2 like 2 (NRF2) signaling in non-small cell lung cancer cell lines with or without Kelch-like ECH-associated protein 1 (KEAP1) mutations and to determine the role of NRF2 and KEAP1 o...

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Detalles Bibliográficos
Autores principales: Tian, Yijun, Wu, Kongming, Liu, Qian, Han, Na, Zhang, Li, Chu, Qian, Chen, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012055/
https://www.ncbi.nlm.nih.gov/pubmed/27601007
http://dx.doi.org/10.1186/s13045-016-0311-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012055/
https://www.ncbi.nlm.nih.gov/pubmed/27601007
http://dx.doi.org/10.1186/s13045-016-0311-0

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