Inhibition of YAP suppresses CML cell proliferation and enhances efficacy of imatinib in vitro and in vivo

BACKGROUND: Yes-associated protein (YAP), an essential component of Hippo pathway, was identified as an oncoprotein which participated in the progression of various malignancies. However, its role in chronic myeloid leukemia (CML) remains to be further clarified. METHODS: The expression of YAP in CM...

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Detalles Bibliográficos
Autores principales: Li, Hui, Huang, Zhenglan, Gao, Miao, Huang, Ningshu, Luo, Zhenhong, Shen, Huawei, Wang, Xin, Wang, Teng, Hu, Jing, Feng, Wenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012077/
https://www.ncbi.nlm.nih.gov/pubmed/27599610
http://dx.doi.org/10.1186/s13046-016-0414-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012077/
https://www.ncbi.nlm.nih.gov/pubmed/27599610
http://dx.doi.org/10.1186/s13046-016-0414-z

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