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Decreased expression of CDH1 or CTNNB1 affects poor prognosis of patients with esophageal cancer

BACKGROUND: E-cadherin/CDH1 is one of the proteins involved in cell adhesion, and it is known that decreased expression of E-cadherin induces lymph node metastasis in esophageal cancer. Beta catenin/CTNNB1, which is an important component of the Wnt signaling pathway, binds to E-cadherin at the cell...

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Detalles Bibliográficos
Autores principales: Ishiguro, Hideyuki, Wakasugi, Takehiro, Terashita, Yukio, Sakamoto, Nobuhiro, Tanaka, Tatsuya, Mizoguchi, Koji, Sagawa, Hiroyuki, Okubo, Tomotaka, Takeyama, Hiromitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012100/
https://www.ncbi.nlm.nih.gov/pubmed/27600761
http://dx.doi.org/10.1186/s12957-016-0956-8