Direct Thrombin Inhibitors Prevent Left Atrial Remodeling Associated With Heart Failure in Rats

The present study tested the hypothesis that thrombin participates in formation of left atrial remodeling and that direct oral anticoagulants, such as direct thrombin inhibitors (DTIs), can prevent its progression. In a rat model of heart failure associated with left atrial dilation, we found that c...

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Detalles Bibliográficos
Autores principales: Jumeau, Céline, Rupin, Alain, Chieng-Yane, Pauline, Mougenot, Nathalie, Zahr, Noël, David-Dufilho, Monique, Hatem, Stéphane N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
PRE-CLINICAL RESEARCH
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012373/
https://www.ncbi.nlm.nih.gov/pubmed/27642643
http://dx.doi.org/10.1016/j.jacbts.2016.05.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012373/
https://www.ncbi.nlm.nih.gov/pubmed/27642643
http://dx.doi.org/10.1016/j.jacbts.2016.05.002

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