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Direct Thrombin Inhibitors Prevent Left Atrial Remodeling Associated With Heart Failure in Rats
The present study tested the hypothesis that thrombin participates in formation of left atrial remodeling and that direct oral anticoagulants, such as direct thrombin inhibitors (DTIs), can prevent its progression. In a rat model of heart failure associated with left atrial dilation, we found that c...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012373/ https://www.ncbi.nlm.nih.gov/pubmed/27642643 http://dx.doi.org/10.1016/j.jacbts.2016.05.002 |