Effective Prevention of Liver Fibrosis by Liver-targeted Hydrodynamic Gene Delivery of Matrix Metalloproteinase-13 in a Rat Liver Fibrosis Model

Liver fibrosis is the final stage of liver diseases that lead to liver failure and cancer. While various diagnostic methods, including the use of serum marker, have been established, no standard therapy has been developed. The objective of this study was to assess the approach of overexpressing matr...

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Detalles Bibliográficos
Autores principales: Abe, Hiroyuki, Kamimura, Kenya, Kobayashi, Yuji, Ohtsuka, Masato, Miura, Hiromi, Ohashi, Riuko, Yokoo, Takeshi, Kanefuji, Tsutomu, Suda, Takeshi, Tsuchida, Masanori, Aoyagi, Yutaka, Zhang, Guisheng, Liu, Dexi, Terai, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012547/
https://www.ncbi.nlm.nih.gov/pubmed/26730813
http://dx.doi.org/10.1038/mtna.2015.49

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012547/
https://www.ncbi.nlm.nih.gov/pubmed/26730813
http://dx.doi.org/10.1038/mtna.2015.49

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