Characterization of MNK1b DNA Aptamers That Inhibit Proliferation in MDA-MB231 Breast Cancer Cells

Elevated expression levels of eukaryotic initiation factor 4E (eIF4E) promote cancer development and progression. MAP kinase interacting kinases (MNKs) modulate the function of eIF4E through the phosphorylation that is necessary for oncogenic transformation. Therefore, pharmacologic MNK inhibitors m...

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Detalles Bibliográficos
Autores principales: García-Recio, Eva M, Pinto-Díez, Celia, Pérez-Morgado, M Isabel, García-Hernández, Marta, Fernández, Gerónimo, Martín, M Elena, González, Víctor M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012548/
https://www.ncbi.nlm.nih.gov/pubmed/26730812
http://dx.doi.org/10.1038/mtna.2015.50

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012548/
https://www.ncbi.nlm.nih.gov/pubmed/26730812
http://dx.doi.org/10.1038/mtna.2015.50

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