A Cell-Based Assay for Measuring Endogenous BcrAbl Kinase Activity and Inhibitor Resistance

Kinase enzymes are an important class of drug targets, particularly in cancer. Cell-based kinase assays are needed to understand how potential kinase inhibitors act on their targets in a physiologically relevant context. Current cell-based kinase assays rely on antibody-based detection of endogenous...

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Detalles Bibliográficos
Autores principales: Ouellette, Steven B., Noel, Brett M., Parker, Laurie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012566/
https://www.ncbi.nlm.nih.gov/pubmed/27598410
http://dx.doi.org/10.1371/journal.pone.0161748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012566/
https://www.ncbi.nlm.nih.gov/pubmed/27598410
http://dx.doi.org/10.1371/journal.pone.0161748

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