Human Cytochrome P450 2W1 Is Not Expressed in Adrenal Cortex and Is Only Rarely Expressed in Adrenocortical Carcinomas

Human cytochome P450 2W1 (CYP2W1) enzyme is expressed in fetal colon and in colon tumors. The level of expression is higher in colon metastases than in the parent tumors and the enzyme is a possible drug target for treatment of colorectal cancer, as demonstrated in mouse xenograft studies. A previou...

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Detalles Bibliográficos
Autores principales: Nolé, Paola, Duijndam, Britt, Stenman, Adam, Juhlin, C. Christofer, Kozyra, Mikael, Larsson, Catharina, Ingelman-Sundberg, Magnus, Johansson, Inger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012573/
https://www.ncbi.nlm.nih.gov/pubmed/27598485
http://dx.doi.org/10.1371/journal.pone.0162379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012573/
https://www.ncbi.nlm.nih.gov/pubmed/27598485
http://dx.doi.org/10.1371/journal.pone.0162379

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