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Chloroquine improves left ventricle diastolic function in streptozotocin-induced diabetic mice

Diabetes is a potent risk factor for heart failure with preserved ejection fraction (HFpEF). Autophagy can be activated under pathological conditions, including diabetic cardiomyopathy. The therapeutic effects of chloroquine (CQ), an autophagy inhibitor, on left ventricle function in streptozotocin...

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Detalles Bibliográficos
Autores principales: Yuan, Xun, Xiao, Yi-Chuan, Zhang, Gui-Ping, Hou, Ning, Wu, Xiao-Qian, Chen, Wen-Liang, Luo, Jian-Dong, Zhang, Gen-Shui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012595/
https://www.ncbi.nlm.nih.gov/pubmed/27621594
http://dx.doi.org/10.2147/DDDT.S111253