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Chloroquine improves left ventricle diastolic function in streptozotocin-induced diabetic mice
Diabetes is a potent risk factor for heart failure with preserved ejection fraction (HFpEF). Autophagy can be activated under pathological conditions, including diabetic cardiomyopathy. The therapeutic effects of chloroquine (CQ), an autophagy inhibitor, on left ventricle function in streptozotocin...
Autores principales: | Yuan, Xun, Xiao, Yi-Chuan, Zhang, Gui-Ping, Hou, Ning, Wu, Xiao-Qian, Chen, Wen-Liang, Luo, Jian-Dong, Zhang, Gen-Shui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012595/ https://www.ncbi.nlm.nih.gov/pubmed/27621594 http://dx.doi.org/10.2147/DDDT.S111253 |
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