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Blocking the Interactions between Calcium-Bound S100A12 Protein and the V Domain of RAGE Using Tranilast

The receptor for advanced glycation end products (RAGE), a transmembrane receptor in the immunoglobulin superfamily, is involved in several inflammatory processes. RAGE induces cellular signaling pathways upon binding with various ligands, such as advanced glycation end products (AGEs), β-amyloids,...

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Detalles Bibliográficos
Autores principales: Chiou, Jian Wei, Fu, Brian, Chou, Ruey-Hwang, Yu, Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012620/
https://www.ncbi.nlm.nih.gov/pubmed/27598566
http://dx.doi.org/10.1371/journal.pone.0162000