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Blocking the Interactions between Calcium-Bound S100A12 Protein and the V Domain of RAGE Using Tranilast
The receptor for advanced glycation end products (RAGE), a transmembrane receptor in the immunoglobulin superfamily, is involved in several inflammatory processes. RAGE induces cellular signaling pathways upon binding with various ligands, such as advanced glycation end products (AGEs), β-amyloids,...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012620/ https://www.ncbi.nlm.nih.gov/pubmed/27598566 http://dx.doi.org/10.1371/journal.pone.0162000 |