Preparation and in vivo evaluation of an orally available enteric-microencapsulated parathyroid hormone (1-34)-deoxycholic acid nanocomplex

The N-terminal 34-amino-acid peptide fragment of human parathyroid hormone PTH (1-34), is used clinically to treat osteoporosis; however, it is currently administered by a once-daily subcutaneous injection, resulting in poor patient compliance. We have developed enteric microcapsules containing an i...

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Detalles Bibliográficos
Autores principales: Hwang, Seung Rim, Seo, Dong-Hyun, Byun, Youngro, Park, Jin Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012625/
https://www.ncbi.nlm.nih.gov/pubmed/27621618
http://dx.doi.org/10.2147/IJN.S110573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012625/
https://www.ncbi.nlm.nih.gov/pubmed/27621618
http://dx.doi.org/10.2147/IJN.S110573

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