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Preparation and in vivo evaluation of an orally available enteric-microencapsulated parathyroid hormone (1-34)-deoxycholic acid nanocomplex
The N-terminal 34-amino-acid peptide fragment of human parathyroid hormone PTH (1-34), is used clinically to treat osteoporosis; however, it is currently administered by a once-daily subcutaneous injection, resulting in poor patient compliance. We have developed enteric microcapsules containing an i...
Autores principales: | Hwang, Seung Rim, Seo, Dong-Hyun, Byun, Youngro, Park, Jin Woo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012625/ https://www.ncbi.nlm.nih.gov/pubmed/27621618 http://dx.doi.org/10.2147/IJN.S110573 |
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