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Intestinal Epithelial Cell-Intrinsic Deletion of Setd7 Identifies Role for Developmental Pathways in Immunity to Helminth Infection

The intestine is a common site for a variety of pathogenic infections. Helminth infections continue to be major causes of disease worldwide, and are a significant burden on health care systems. Lysine methyltransferases are part of a family of novel attractive targets for drug discovery. SETD7 is a...

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Detalles Bibliográficos
Autores principales: Oudhoff, Menno J., Antignano, Frann, Chenery, Alistair L., Burrows, Kyle, Redpath, Stephen A., Braam, Mitchell J., Perona-Wright, Georgia, Zaph, Colby
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012677/
https://www.ncbi.nlm.nih.gov/pubmed/27598373
http://dx.doi.org/10.1371/journal.ppat.1005876