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Assessment of Telomere Length in Archived Formalin-Fixed, Paraffinized Human Tissue Is Confounded by Chronological Age and Storage Duration

Telomeres shorten with physiological aging but undergo substantial restoration during cancer immortalization. Increasingly, cancer studies utilize the archive of formalin-fixed, paraffin-embedded (FFPE) tissues in diagnostic pathology departments. Conceptually, such studies would be confounded by ph...

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Detalles Bibliográficos
Autores principales: Kong, Po-Lian, Looi, Lai-Meng, Lau, Tze-Pheng, Cheah, Phaik-Leng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012687/
https://www.ncbi.nlm.nih.gov/pubmed/27598341
http://dx.doi.org/10.1371/journal.pone.0161720