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Assessment of Telomere Length in Archived Formalin-Fixed, Paraffinized Human Tissue Is Confounded by Chronological Age and Storage Duration
Telomeres shorten with physiological aging but undergo substantial restoration during cancer immortalization. Increasingly, cancer studies utilize the archive of formalin-fixed, paraffin-embedded (FFPE) tissues in diagnostic pathology departments. Conceptually, such studies would be confounded by ph...
Autores principales: | Kong, Po-Lian, Looi, Lai-Meng, Lau, Tze-Pheng, Cheah, Phaik-Leng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012687/ https://www.ncbi.nlm.nih.gov/pubmed/27598341 http://dx.doi.org/10.1371/journal.pone.0161720 |
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