Qualitative Dynamical Modelling Can Formally Explain Mesoderm Specification and Predict Novel Developmental Phenotypes

Given the complexity of developmental networks, it is often difficult to predict the effect of genetic perturbations, even within coding genes. Regulatory factors generally have pleiotropic effects, exhibit partially redundant roles, and regulate highly interconnected pathways with ample cross-talk....

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Detalles Bibliográficos
Autores principales: Mbodj, Abibatou, Gustafson, E. Hilary, Ciglar, Lucia, Junion, Guillaume, Gonzalez, Aitor, Girardot, Charles, Perrin, Laurent, Furlong, Eileen E. M., Thieffry, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012701/
https://www.ncbi.nlm.nih.gov/pubmed/27599298
http://dx.doi.org/10.1371/journal.pcbi.1005073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012701/
https://www.ncbi.nlm.nih.gov/pubmed/27599298
http://dx.doi.org/10.1371/journal.pcbi.1005073

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