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Nasal Absorption of Macromolecules from Powder Formulations and Effects of Sodium Carboxymethyl Cellulose on Their Absorption

The nasal absorption of macromolecules from powder formulations and the effect of sodium carboxymethyl cellulose (CMC-Na) as a pharmaceutical excipient on their absorption were studied. Model macromolecules were fluorescein isothiocyanate-labeled dextran (average molecular weight of 4.4kDa, FD4) and...

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Detalles Bibliográficos
Autores principales: Tanaka, Akiko, Furubayashi, Tomoyuki, Matsushita, Akifumi, Inoue, Daisuke, Kimura, Shunsuke, Katsumi, Hidemasa, Sakane, Toshiyasu, Yamamoto, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012702/
https://www.ncbi.nlm.nih.gov/pubmed/27598527
http://dx.doi.org/10.1371/journal.pone.0159150