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Nasal Absorption of Macromolecules from Powder Formulations and Effects of Sodium Carboxymethyl Cellulose on Their Absorption
The nasal absorption of macromolecules from powder formulations and the effect of sodium carboxymethyl cellulose (CMC-Na) as a pharmaceutical excipient on their absorption were studied. Model macromolecules were fluorescein isothiocyanate-labeled dextran (average molecular weight of 4.4kDa, FD4) and...
Autores principales: | Tanaka, Akiko, Furubayashi, Tomoyuki, Matsushita, Akifumi, Inoue, Daisuke, Kimura, Shunsuke, Katsumi, Hidemasa, Sakane, Toshiyasu, Yamamoto, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012702/ https://www.ncbi.nlm.nih.gov/pubmed/27598527 http://dx.doi.org/10.1371/journal.pone.0159150 |
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