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Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes

The apolipoprotein E (APOE) gene is the most highly associated susceptibility locus for late onset Alzheimer’s Disease (AD), and augmenting the beneficial physiological functions of apoE is a proposed therapeutic strategy. In a high throughput phenotypic screen for small molecules that enhance apoE...

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Detalles Bibliográficos
Autores principales: Fan, Jianjia, Zareyan, Shahab, Zhao, Wenchen, Shimizu, Yoko, Pfeifer, Tom A., Tak, Jun-Hyung, Isman, Murray B., Van den Hoven, Bernard, Duggan, Mark E., Wood, Michael W., Wellington, Cheryl L., Kulic, Iva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012716/
https://www.ncbi.nlm.nih.gov/pubmed/27598782
http://dx.doi.org/10.1371/journal.pone.0162384