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Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes
The apolipoprotein E (APOE) gene is the most highly associated susceptibility locus for late onset Alzheimer’s Disease (AD), and augmenting the beneficial physiological functions of apoE is a proposed therapeutic strategy. In a high throughput phenotypic screen for small molecules that enhance apoE...
Autores principales: | Fan, Jianjia, Zareyan, Shahab, Zhao, Wenchen, Shimizu, Yoko, Pfeifer, Tom A., Tak, Jun-Hyung, Isman, Murray B., Van den Hoven, Bernard, Duggan, Mark E., Wood, Michael W., Wellington, Cheryl L., Kulic, Iva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012716/ https://www.ncbi.nlm.nih.gov/pubmed/27598782 http://dx.doi.org/10.1371/journal.pone.0162384 |
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