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Insulin signaling controls neurotransmission via the 4eBP-dependent modification of the exocytotic machinery

Altered insulin signaling has been linked to widespread nervous system dysfunction including cognitive dysfunction, neuropathy and susceptibility to neurodegenerative disease. However, knowledge of the cellular mechanisms underlying the effects of insulin on neuronal function is incomplete. Here, we...

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Detalles Bibliográficos
Autores principales: Mahoney, Rebekah Elizabeth, Azpurua, Jorge, Eaton, Benjamin A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012858/
https://www.ncbi.nlm.nih.gov/pubmed/27525480
http://dx.doi.org/10.7554/eLife.16807