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Isoegomaketone Upregulates Heme Oxygenase-1 in RAW264.7 Cells via ROS/p38 MAPK/Nrf2 Pathway

Isoegomaketone (IK) was isolated from Perilla frutescens, which has been widely used as a food in Asian cuisine, and evaluated for its biological activity. We have already confirmed that IK induced the HO-1 expression via Nrf2 activation in RAW264.7 cells. In this study, we investigated the effect o...

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Detalles Bibliográficos
Autores principales: Jin, Chang Hyun, So, Yang Kang, Han, Sung Nim, Kim, Jin-Baek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012876/
https://www.ncbi.nlm.nih.gov/pubmed/27582555
http://dx.doi.org/10.4062/biomolther.2015.194