Cargando…

Isoegomaketone Upregulates Heme Oxygenase-1 in RAW264.7 Cells via ROS/p38 MAPK/Nrf2 Pathway

Isoegomaketone (IK) was isolated from Perilla frutescens, which has been widely used as a food in Asian cuisine, and evaluated for its biological activity. We have already confirmed that IK induced the HO-1 expression via Nrf2 activation in RAW264.7 cells. In this study, we investigated the effect o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jin, Chang Hyun, So, Yang Kang, Han, Sung Nim, Kim, Jin-Baek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012876/ https://www.ncbi.nlm.nih.gov/pubmed/27582555 http://dx.doi.org/10.4062/biomolther.2015.194

Ejemplares similares

9-Hydroxy-isoegomaketone inhibits LPS-induced NO and inflammatory cytokine production in RAW264.7 cells
por: Kim, Hyun Mi, et al.
Publicado: (2021)

Dimethoxycurcumin, a Synthetic Curcumin Analogue, Induces Heme Oxygenase-1 Expression through Nrf2 Activation in RAW264.7 Macrophages
por: Jeong, Sun-Oh, et al.
Publicado: (2009)

Silibinin Inhibits LPS-Induced Macrophage Activation by Blocking p38 MAPK in RAW 264.7 Cells
por: Youn, Cha Kyung, et al.
Publicado: (2013)

YJI-7 Suppresses ROS Production and Expression of Inflammatory Mediators via Modulation of p38MAPK and JNK Signaling in RAW 264.7 Macrophages
por: Oh, Hye Jin, et al.
Publicado: (2018)

Melatonin induces RAW264.7 cell apoptosis via the BMAL1/ROS/MAPK-p38 pathway to improve postmenopausal osteoporosis
por: Wang, Xiaochuan, et al.
Publicado: (2023)

Andrographolide induces Nrf2 and heme oxygenase 1 in astrocytes by activating p38 MAPK and ERK
por: Wong, Siew Ying, et al.
Publicado: (2016)

Isoegomaketone Alleviates the Development of Collagen Antibody-Induced Arthritis in Male Balb/c Mice
por: Jin, Chang Hyun, et al.
Publicado: (2017)

Anti-Inflammatory Activity and ROS Regulation Effect of Sinapaldehyde in LPS-Stimulated RAW 264.7 Macrophages
por: Baek, Seung-Hwa, et al.
Publicado: (2020)

Anti-inflammatory effects of extracellular vesicles from Morchella on LPS-stimulated RAW264.7 cells via the ROS-mediated p38 MAPK signaling pathway
por: Chen, Qi, et al.
Publicado: (2022)

Dysiarenone from Marine Sponge Dysidea arenaria Attenuates ROS and Inflammation via Inhibition of 5-LOX/NF-κB/MAPKs and Upregulation of Nrf-2/OH-1 in RAW 264.7 Macrophages
por: Hu, Tian-Yong, et al.
Publicado: (2021)

Genistein Inhibits Osteoclastic Differentiation of RAW 264.7 Cells via Regulation of ROS Production and Scavenging
por: Lee, Sang-Hyun, et al.
Publicado: (2014)

The uptake of tocopherols by RAW 264.7 macrophages
por: Gao, Rong, et al.
Publicado: (2002)

Immunostimulatory Effect of Laminarin on RAW 264.7 Mouse Macrophages
por: Lee, Ji Young, et al.
Publicado: (2012)

The Heme Oxygenase-1 Inducer THI-56 Negatively Regulates iNOS Expression and HMGB1 Release in LPS-Activated RAW 264.7 Cells and CLP-Induced Septic Mice
por: Park, Eun Jung, et al.
Publicado: (2013)

Factors that Affect the Osteoclastogenesis of RAW264.7 Cells
por: Nguyen, John, et al.
Publicado: (2017)

Fermented Sea Tangle (Laminaria japonica Aresch) Suppresses RANKL-Induced Osteoclastogenesis by Scavenging ROS in RAW 264.7 Cells
por: Jeong, Jin-Woo, et al.
Publicado: (2019)

Protective Effect of Glutathione against Oxidative Stress-induced Cytotoxicity in RAW 264.7 Macrophages through Activating the Nuclear Factor Erythroid 2-Related Factor-2/Heme Oxygenase-1 Pathway
por: Kwon, Da Hye, et al.
Publicado: (2019)

Anti-oxidizing effect of the dichloromethane and hexane fractions from Orostachys japonicus in LPS-stimulated RAW 264.7 cells via upregulation of Nrf2 expression and activation of MAPK signaling pathway
por: Lee, Hyeong-Seon, et al.
Publicado: (2014)

Isoegomaketone from Perilla frutescens (L.) Britt Stimulates MAPK/ERK Pathway in Human Keratinocyte to Promote Skin Wound Healing
por: Kim, Ye-Ram, et al.
Publicado: (2021)

Suppression of Heme Oxygenase-1 by Prostaglandin E(2)-Protein Kinase A-A-Kinase Anchoring Protein Signaling Is Central for Augmented Cyclooxygenase-2 Expression in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages
por: Lee, Jae-Hyoung, et al.
Publicado: (2013)

Antioxidative Effects of Thymus quinquecostatus CELAK through Mitochondrial Biogenesis Improvement in RAW 264.7 Macrophages
por: Hong, Jin Young, et al.
Publicado: (2020)

Immune-Stimulatory Effects of Althaea rosea Flower Extracts through the MAPK Signaling Pathway in RAW264.7 Cells
por: Kim, Yon-Suk, et al.
Publicado: (2017)

Heracleum moellendorffii roots inhibit the production of pro-inflammatory mediators through the inhibition of NF-κB and MAPK signaling, and activation of ROS/Nrf2/HO-1 signaling in LPS-stimulated RAW264.7 cells
por: Kim, Ha Na, et al.
Publicado: (2019)

Celastrol inhibits hepatitis C virus replication by upregulating heme oxygenase-1 via the JNK MAPK/Nrf2 pathway in human hepatoma cells
por: Tseng, Chin-Kai, et al.
Publicado: (2017)

Immunomodulatory Effects of N-Acetyl Chitooligosaccharides on RAW264.7 Macrophages
por: Deng, Jun-Jin, et al.
Publicado: (2020)

Immunostimulatory Effect of Heat-Killed Probiotics on RAW264.7 Macrophages
por: Noh, Hye-Ji, et al.
Publicado: (2022)

Okanin, a chalcone found in the genus Bidens, and 3-penten-2-one inhibit inducible nitric oxide synthase expression via heme oxygenase-1 induction in RAW264.7 macrophages activated with lipopolysaccharide
por: Kil, Jin-Sang, et al.
Publicado: (2012)

Inhibitory Effects of Benzaldehyde Derivatives from the Marine Fungus Eurotium sp. SF-5989 on Inflammatory Mediators via the Induction of Heme Oxygenase-1 in Lipopolysaccharide-Stimulated RAW264.7 Macrophages
por: Kim, Kyoung-Su, et al.
Publicado: (2014)

Neuroprotective and Anti-Inflammatory Effects of Kuwanon C from Cudrania tricuspidata Are Mediated by Heme Oxygenase-1 in HT22 Hippocampal Cells, RAW264.7 Macrophage, and BV2 Microglia
por: Ko, Wonmin, et al.
Publicado: (2020)

Japanese Encephalitis Virus Upregulates the Expression of SOCS3 in Mouse Brain and Raw264.7 Cells
por: Li, Xiangmin, et al.
Publicado: (2014)

Hypochoeris radicata attenuates LPS-induced inflammation by suppressing p38, ERK, and JNK phosphorylation in RAW 264.7 macrophages
por: Kim, Min-Jin, et al.
Publicado: (2014)

Anti-Inflammatory Effects of Spiramycin in LPS-Activated RAW 264.7 Macrophages
por: Kang, Jin-Kyu, et al.
Publicado: (2022)

Adseverin knockdown inhibits osteoclastogenesis in RAW264.7 cells
por: QI, WENTING, et al.
Publicado: (2014)

Sesamin Enhances Cholesterol Efflux in RAW264.7 Macrophages
por: Liu, Nan, et al.
Publicado: (2014)

Overview of RAW264.7 for osteoclastogensis study: Phenotype and stimuli
por: Kong, Lingbo, et al.
Publicado: (2019)

Inductive Effect of Palmatine on Apoptosis in RAW 264.7 Cells
por: Ishikawa, Shintaro, et al.
Publicado: (2016)

Evaluation of culture conditions for osteoclastogenesis in RAW264.7 cells
por: Cheng, Yin, et al.
Publicado: (2022)

Monascin abrogates RANKL-mediated osteoclastogenesis in RAW264.7 cells via regulating MAPKs signaling pathways
por: Cheng, Yin, et al.
Publicado: (2022)

Protective Effects of Fermented Oyster Extract against RANKL-Induced Osteoclastogenesis through Scavenging ROS Generation in RAW 264.7 Cells
por: Jeong, Jin-Woo, et al.
Publicado: (2019)

β-Lapachone, a substrate of NAD(P)H:quinone oxidoreductase, induces anti-inflammatory heme oxygenase-1 via AMP-activated protein kinase activation in RAW264.7 macrophages
por: Byun, Seung Jae, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_gof47tr50muuud7op2aiv07458